Patients’ and urologists’ preferences for prostate cancer treatment: a discrete choice experiment

  • Bas Donkers Bas Donkers
  • Chris Bangma Chris Bangma
  • Esther de Bekker-Grob Esther de Bekker-Grob
  • Ewout Steyerberg Ewout Steyerberg
  • I.J. Korfage I.J. Korfage
  • M.C.J. Bliemer M.C.J. Bliemer
  • Marie-Louise Essink-Bot Marie-Louise Essink-Bot
  • Monica Joanne Roobol-Bouts Monica Joanne Roobol-Bouts

Background:Patients’ preferences are important for shared decision making. Therefore, we investigated patients’ and urologists’ preferences for treatment alternatives for early prostate cancer (PC).Methods:A discrete choice experiment was conducted among 150 patients who were waiting for their biopsy results, and 150 urologists. Regression analysis was used to determine patients’ and urologists’ stated preferences using scenarios based on PC treatment modality (radiotherapy, surgery, and active surveillance (AS)), and risks of urinary incontinence and erectile dysfunction.Results:The response rate was 110 out of 150 (73%) for patients and 50 out of 150 (33%) for urologists. Risk of urinary incontinence was an important determinant of both patients’ and urologists’ stated preferences for PC treatment (P<0.05). Treatment modality also influenced patients’ stated preferences (P<0.05), whereas the risk of erectile dysfunction due to radiotherapy was mainly important to urologists (P<0.05). Both patients and urologists preferred AS to radical treatment, with the exception of patients with anxious/depressed feelings who preferred radical treatment to AS.Conclusion:Although patients and urologists generally may prefer similar treatments for PC, they showed different trade-offs between various specific treatment aspects. This implies that urologists need to be aware of potential differences compared with the patient’s perspective on treatment decisions in shared decision making on PC treatment.

Netspar, Network for Studies on Pensions, Aging and Retirement, is a thinktank and knowledge network. Netspar is dedicated to promoting a wider understanding of the economic and social implications of pensions, aging and retirement in the Netherlands and Europe.


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